Криоконсервация репродуктивного материала у онкологических больных

Назаренко Т.А., Бурдули А.Г., Мартиросян Я.О., Джанашвили Л.Г.

ФГБУ «Национальный медицинский исследовательский центр акушерства, гинекологии и перинатологии имени В.И. Кулакова» Минздрава России, Москва, Россия
В обзор включены данные зарубежных и отечественных статей, найденных в PubMed по рассматриваемой теме и опубликованных в последние годы. Обсуждается современное состояние проблемы сохранения репродуктивного материала у онкологических больных молодого возраста. Подчеркивается необходимость расширения и интенсификации исследований в области онкофертильности вследствие растущей клинической потребности и нерешенности многих задач. В статье рассмотрены предлагаемые способы защиты яичников перед химио-/лучевой терапией, современные методики получения и консервации ооцитов/эмбрионов, определены протоколы стимуляции яичников, их эффективность и безопасность. Приведены данные об экспериментальных направлениях в
этой области и перспективах их использования в клинической практике.

Ключевые слова

онкологические больные
сохранение репродуктивного материала
онкофертильность
криоконсервация
ооциты
эмбрионы
ткань яичника
аутотрансплантация
созревание in vitro

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Поступила 25.03.2019

Принята в печать 19.04.2019

Об авторах / Для корреспонденции

Назаренко Татьяна Алексеевна, д.м.н., профессор, директор института репродуктивной медицины ФГБУ «НМИЦ АГП им. академика В.И. Кулакова» МЗ России.
Тел.: +7 (495)4381341. E-mail: t.nazarenko@mail.ru. Адрес: 117997, Россия, ул. Академика Опарина, д. 4.
Бурдули Анна Георгиевна, к.м.н., с.н.с. отделения вспомогательных технологий в лечении бесплодия им. Б.В. Леонова ФГБУ «НМИЦ АГП им. академика В.И. Кулакова» Минздрава России. Тел.: +7 (495)5314444. E-mail: burdulianna@gmail.com
Адрес: 117997, Россия, ул. Академика Опарина, д. 4.
Мартиросян Яна Ованнесовна, ординатор ФГБУ «НМИЦ АГП им. академика В.И. Кулакова» МЗ России. Тел.: +7(916)9500745. E-mail: marti-yana@index.ru
Адрес: 117997, Россия, ул. Академика Опарина, д. 4.
Джанашвили Лана Георгиевна, аспирант ФГБУ «НМИЦ АГП им. академика В.И. Кулакова» МЗ России. Тел. +7 (962)918-5619. E-mail: lana.janashvili@gmail.com
Адрес: 117997, Россия, ул. Академика Опарина, д. 4.

Для цитирования: Назаренко Т.А., Бурдули А.Г., Мартиросян Я.О., Джанашвили Л.Г. Криоконсервация репродуктивного материала у онкологических больных.
Акушерство и гинекология. 2019; 9:40-9.
https://dx.doi.org/10.18565/aig.2019.9.40-49

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