Sociomedical characteristics of HIV-infected patients in IVF programs

Isakova K.M., Nazarenko T.A., Krasnopolskaya K.V.

Moscow Research Institute of Obstetrics and Gynecology, Moscow 101000, Pokrovka str. 22a, Russia
Objective. To investigate the sociomedical characteristics of HIV-infected patients and the features of their reproductive history and reproductive behavior.
Subjects and methods. The bulk of HIV-infected patients who sought advice for IVF treatment programs was HIV-serodiscordant couples with an infected male, there were 64 (65%) and 39 (35%) infected men and women, respectively.
Results. Out of the examinees, 68.7% of the men were infected parenterally due to drug use; 28.2% of the women were infected via drug use, which shows that parenteral infection remains to be of paramount importance in more than half of the men and in one third of the women. The social characteristics of the examinees demonstrated their social adaptability when the vast majority had education, employment, steady income, and place of residence. The HIV-positive women were found to have negative reproductive behavior factors and poor reproductive and gynecological health. Thus, only 9% of the HIV-serodiscordant couples regularly used contraception; every three women had abortions; more than half of the patients had a history of pelvic inflammatory diseases, cervical diseases, ectopic pregnancies, miscarriage, and infertility.
Conclusion. Conclusions are drawn concerning the necessity of broadening the scope of examining HIV-infected patients, as well as a careful analysis of their social characteristics and reproductive history.

Keywords

serodiscordant
seroconcordant couples
HIV infection
viral RNA
CD4+
antiretroviral therapy
IVF programs

References

1. Гузенкова С., Петровская О.В., Белобородов И.И. Социальные аспекты противодействия ВИЧ-инфекции в мегаполисах (на примере Москвы). Аналитический доклад РИСИ. М.; 2016. [Guzenkova S., Petrovskaya O.V., Beloborodov I.I. Social aspects of counteracting HIV infection in megacities (on the example of Moscow). Analytical report of RISI. Moscow; 2016. (in Russian)]

2. Портнов И.Г., Назаренко Т.А., Балезин С.Ф., Иванов А.В., Квашнина Е.В., Киреев Д.Е., Кузмин А.В., Куевда Д.А., Лопатухин А.Э., Шипулин Г.А., Турчанинова Е.В. Обоснование и принципы организации специализированного отделения вспомогательных репродуктивных технологий (ВРТ) для пациенток с ВИЧ-инфекцией. Проблемы репродукции. 2012; Специальный выпуск: VI Международный конгресс по репродуктивной медицине: 17-8. [Portnov I.G., Nazarenko T.A., Balezin S.F., Ivanov A.V., Kvashnina E.V., Kireev D.E., Kuzmin A.V., Kuevda D.A., Lopatuhin A.E., Shipulin G.A., Turchaninova E.V. Rationale and principles of the organization of a specialized branch of assisted reproductive technologies (ART) for patients with HIV infection. Reproduction problems. 2012; Special issue: VI International Congress on Reproductive Medicine: 17-8. (in Russian)]

3. Беляков Н.А., Рахманова А.Г., ред. Вирус иммунодефицита человека – медицина. Руководство для врачей. 2-е изд. СПб.: Балтийский медицинский образовательный центр; 2011. 656с. [Belyakov N.A., Rahmanova A.G., ed. Human immunodeficiency virus – medicine. A guide for doctors. 2nd ed. St. Petersburg: Baltic Medical Education Center; 2011. 656p. (in Russian)]

4. Покровский В.В., ред. ВИЧ-инфекция и СПИД. 2-е изд. М.: ГЭОТАР-Медиа; 2010. 192с. [Pokrovskiy V.V., ed. HIV infection and AIDS. 2 nd ed. Moscow: GEOTAR-Media; 2010. 192p. (in Russian)]

5. Соколова Е.В., Покровский В.В., Ладная Н.Н. Ситуация по ВИЧ-инфекции в Российской Федерации. Терапевтический архив. 2013; 85(11): 10-5. [Sokolova E.V., Pokrovskiy V.V., Ladnaya N.N. The situation of HIV in the Russian Federation. Terapevticheskiy arhiv. 2013; 85(11): 10-5. (in Russian)]

6. Tai H., Udoji M.A., Barkanic G., Byrne D.W., Rebeiro P.F., Byram B.R. et al. Pregnancy and HIV disease progression during the era of highly active antiretroviral therapy. J. Infect. Dis. 2007; 196(7): 1044-52.

7. Van Leeuwen E., De Witt F.W., Repping S., Eeftinkl Schattenkerk J.K., Reiss P., van der Veen F., Prins J.M. Effects of antiretroviral therapy on semen quality. AIDS. 2008; 22(5): 637-42.

8. Никитин С.В., Мусатов В.Б. Вспомогательные методы репродукции и ВИЧ. Проблемы репродукции. 2009; Специальный выпуск: III Международный конгресс по репродуктивной медицине: 286. [Nikitin S.V., Musatov V.B. Supportive methods of reproduction and HIV. Reproduction problems. 2009; Special issue: III International Congress on Reproductive Medicine: 286. (in Russian)]

9. Гафуров Ю.Т., Краснопольская К.В., Назаренко Т.А., Сундуков А.В. Особенности патологии шейки матки у больных с ВИЧ-инфекцией. Российский вестник акушера-гинеколога. 2013; 13(1): 17-22. [Gafurov Yu.T., Krasnopolskaya K.V., Nazarenko T.A., Sundukov A.V. Features of the pathology of the cervix in patients with HIV infection. Rossiyskiy vestnik akushera-ginekologa. 2013; 13(1): 17-22. (in Russian)]

Received 06.03.2017

Accepted 28.04.2017

About the Authors

Nazarenko Tatyana Alekseevna, Doctor of Medical Sciences, Professor, Chief Researcher, Moscow Research Institute of Obstetrics and Gynecology.
101000, Russia, Moscow, Pokrovka str. 22a. Tel.: +74956222233. E-mail: t.nazarenko@mail.ru
Kraslopolskaya Ksenia Vladislavovna, MD, Head of the Department of Reproductology, Moscow Research Institute of Obstetrics and Gynecology.
101000, Russia, Moscow, Pokrovka str. 22a. Tel.: +74956222233. E-mail: biooptima@gmail.com
Isakova Kamila Muslimovna, Postgraduate Student, Department of Reproduction, Moscow Research Institute of Obstetrics and Gynecology.
101000, Russia, Moscow, Pokrovka str. 22a. Tel.: +74956222233. E-mail: isa-kama@yandex.ru

For citations: Isakova K.M., Nazarenko T.A., Krasnopolskaya K.V. Sociomedical characteristics of HIV-infected patients in IVF programs. Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2017; (11): 100-6. (in Russian)
https://dx.doi.org/10.18565/aig.2017.11.100-106

Similar Articles

By continuing to use our site, you consent to the processing of cookies that ensure the proper functioning of the site.