Clinical and laboratory assessment of ovarian reserve from a reproductologist’s point of view

Marchenko L.A. Mashaeva, R.I.

National Medical Research Center of Obstetrics, Gynecology, and Perinatology Academician named after V.I. Kulakov, Ministry of Health of Russia, Moscow 117997, Ac. Oparina str. 4, Russia
The data available in the modern literature on the diagnostic capabilities of current clinical and laboratory markers of ovarian reserve undergo systems analysis. The diagnostic capabilities of current clinical and laboratory markers of ovarian reserve, which reflect the primordial pool of follicles and predictors involved in predicting the onset of spontaneous pregnancy and premature ovarian aging, are discussed. To date, there is no single global consensus for the best test to accurately assess the quantity and quality of eggs. It is necessary to conduct full-scale multicenter, prospective, randomized, controlled studies, the results of which would facilitate the consultation of patients and assist a clinician in drawing an individual treatment plan.

Keywords

premature ovarian failure (POF)
anti-Müllerian hormone (AMH)
diminished ovarian reserve (ROR)
poor ovarian response (POR)

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Received 21.11.2017

Accepted 22.12.2017

About the Authors

Marchenko, Larisa A., MD, Professor, Leading Research Associate, Gynecological Endocrinology Department, National Medical Research Center of Obstetrics,
Gynecology, and Perinatology Academician named after V.I. Kulakov, Ministry of Health of Russia.
117997, Russia, Moscow, Ac. Oparina str. 4. Tel.: +74954388540. E-mail: l.a.marchenko@yandex.ru
Mashaeva, Roza I., postgraduate student of the department of gynecological endocrinology, National Medical Research Center of Obstetrics, Gynecology, and Perinatology Academician named after V.I. Kulakov, Ministry of Health of Russia. 117997, Russia, Moscow, Ac. Oparina str. 4. Tel.: +79099336476. E-mail: mashaevarosa@gmail.com

For citations: Marchenko L.A., Mashaeva R.I. Clinical and laboratory assessment of ovarian reserve from a reproductologist’s point of view . Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2018; (8): 22-5. (in Russian)
https://dx.doi.org/10.18565/aig.2018.8.22-25

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