Андрогенный дефицит у женщин различного возраста: диагностика и терапия
Проанализированы литературные данные о метаболизме андрогенов в женском организме, их влиянии на фолликуло- и оогенез и сексуальную функцию женщин различного возраста. Освещены вопросы диагностики недостаточности андрогенов и причины ее возникновения. Изучены вопросы применения андрогенов в терапии, применяемой в программах вспомогательных репродуктивных технологий, при надпочечниковой недостаточности и в постменопаузе. Дальнейшие исследования должны быть направлены на определение четких показаний для проведения терапии андрогенами, наиболее подходящего пути введения лекарственного препарата и его дозировки.Романов А.Ю., Гависова А.А., Долгушина Н.В.
Ключевые слова
андрогенный дефицит
терапия андрогенами
бесплодие
фолликулогенез
оогенез
недостаточность надпочечников
менопауза
тестостерон
дегидроэпиандростерон
дегидроэпиандростерон-сульфат
андростендион
5α-дигидротестостерон
вспомогательные репродуктивные технологии
экстракорпоральное оплодотворение
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Поступила 18.11.2019
Принята в печать 29.11.2019
Об авторах / Для корреспонденции
Романов Андрей Юрьевич, аспирант, специалист отдела наукометрии департамента организации научной деятельности ФГБУ «НМИЦ АГП им. акад. В.И. Кулакова» Минздрава России. Тел.: +7(903) 58-94-00. E-mail: romanov1553@yandex.ru. 117997, Россия, Москва, ул. Академика Опарина, д. 4.Гависова Алла Анатольевна, к.м.н., старший научный сотрудник 1-го гинекологического отделения ФГБУ «НМИЦ АГП им. акад. В.И. Кулакова» Минздрава России. E-mail: gavialla@yandex.ru. 117997, Россия, Москва, ул. Академика Опарина, д. 4.
Долгушина Наталия Витальевна, д.м.н., профессор, заместитель директора – руководитель департамента организации научной деятельности ФГБУ «НМИЦ АГП
им. акад. В.И. Кулакова» Минздрава России. E-mail: n_dolgushina@oparina4.ru. 117997, Россия, Москва, ул. Академика Опарина, д. 4.
Для цитирования: Романов А.Ю., Гависова А.А., Долгушина Н.В.
Андрогенный дефицит у женщин различного возраста: диагностика и терапия.
Акушерство и гинекология. 2020; 5: 58-64
https://dx.doi.org/10.18565/aig.2020.5.58-64