Biochemical tests for the diagnosis of high risk of preterm birth
According to the results of clinical studies published in the English and Russian literature in open databases the author has determined the significance and effectiveness of biochemical tests for the diagnosis of preterm birth.The definition of PAMG-1 for the diagnosis of preterm labor has sensitivity values of 84%, specificity is 95%, positive predictive value is 77% and negative prognosis is 97% and is a more reliable method than determining fFN, fPSIFR-1 or measuring cervical length and is associated with a reduction in financial costs. The use of the test kit for determining PAMG-1 is the most effective in comparison with other methods and allows to avoiding incorrect diagnosis and unnecessary hospitalization.Dikke G.B.
Keywords
premature birth
cervical length
fFN
fPSIF-1
PAMG-1
References
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Received 08.06.2018
Accepted 22.06.2018
About the Authors
Dikke Galina B., MD, Professor of the Department of Obstetrics, Gynecology and Reproductive Medicine, Faculty of Postgraduate Education of Medical Workersof the Medical Institute, Peoples’ Friendship University of Russia, Ministry of Education and Science of the Russian Federation.
117198, Russia, Moscow, Miklukho-Maklaya str. 6. Tel.: +79265280383. E-mail: galadikke@yandex.ru
For citations: Dikke G.B. Biochemical tests for the diagnosis of high risk of preterm birth. Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2018; (7): 108-13. (in Russian)
https://dx.doi.org/10.18565/aig.2018.7.108-113
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