Influence of seminal plasma on female reproductive function

Dontsova T.V., Kalinina E.A., Nikolaeva M.A., Babayan A.A., Alieva K.U.

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia, Moscow 117997, Ac. Oparina str. 4, Russia
Objective. To carry out a systematic analysis of the data available in the current literature on the influence of seminal plasma on the occurrence of pregnancy and its role in the physiology of the female reproductive system.
Material and methods. The review includes the data of foreign and Russian articles published in the past 10 years and found in Pubmed on this topic.
Results. The paper reviews publications concerning the study of the influence of seminal plasma on the female reproductive tract and considers signaling molecules and various mechanisms of their action.
Conclusion. A deep understanding of the molecular and cellular bases of the effect of seminal plasma on the formation of a maternal optimal immune response that is necessary for the successful realization of reproductive function will be able allow to elaborate new personalized approaches to treating infertility and pregnancy disorders and planning a family.

Keywords

seminal plasma
infertility
in vitro fertilization
embryo implantation
cytokines

References

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Received 09.12.2016

Accepted 23.12.2016

About the Authors

Dontsova Tatyana Vladimirovna, postgraduate student of the Department of Auxiliary Technologies in Infertility Treatment, Research Center of Obstetrics,
Gynecology, and Perinatology, Ministry of Health of Russia. 117997, Russia, Moscow, Ac. Oparina str. 4. Tel.: +74954382501. E-mail: dr.dontsova@gmail.com
Kalinina Elena Anatolievna, MD, Head of the Department of Auxiliary Technologies in Infertility Treatment, Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia. 117997, Russia, Moscow, Ac. Oparina str. 4. Tel.: +74954381341. E-mail: e_kalinina@oparina4.ru
Nikolaeva Marina Arkadevna, Doctor of Biological Sciences, Leading Researcher of the Laboratory of Clinical Immunology, Research Center of Obstetrics,
Gynecology, and Perinatology, Ministry of Health of Russia. 117997, Russia, Moscow, Ac. Oparina str. 4. Tel.: +74954381341. E-mail: nikolaeva_ma@mail.ru
Babayan Alina Anatolievna, doctor of the Department of Auxiliary Technologies in Infertility Treatment, Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia. 117997, Russia, Moscow, Ac. Oparina str. 4. Tel.: +74954382501. E-mail: alinababayan@yandex.ru
Aliyeva Kamila Ullubievna, Ph.D., scientific employee of the Department of Auxiliary Technologies in Infertility Treatment, Research Center of Obstetrics,
Gynecology, and Perinatology, Ministry of Health of Russia. 117997, Russia, Moscow, Ac. Oparina str. 4. Tel.: +74954381341. E-mail: kaya79@mail.ru

For citations: Dontsova T.V., Kalinina E.A., Nikolaeva M.A., Babayan A.A., Alieva K.U.
Influence of seminal plasma on female reproductive function.
Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2017; (10): 20-5. (in Russian)
https://dx.doi.org/10.18565/aig.2017.10.20-25

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