Evaluation of the clinical efficiency of antiviral therapy for recurrent genital herpes

Pestrikova T.Yu., Yurasova E.A., Kovaleva T.D., Voronova Yu.V., Kotelnikova A.V.

Far Eastern State Medical University, Ministry of Health of Russia, Khabarovsk 680000, Muravyeva-Amurskogo str. 35, Russia
Objective. To evaluate the efficacy of Valvir (valacyclovir) in the treatment of patients with recurrent genital herpes.
Subjects and methods. The study covered 34 patients aged from 18 to 35 years, in whom the diagnosis of recurrent genital herpes was verified according to clinical and laboratory findings. The clinical efficiency of antiviral therapy was evaluated in the patients during 3 gynecology visits.
Results. The findings suggest that disappearance of herpetic rashes and healing of focal lesions occurred with a high degree of statistical significance on day 4 of treatment. The area of affected foci with residual phenomena of herpetic rashes was decreased by 75% or more of the initial value at follow-up day 6. The duration of a recurrent genital herpes episode was reduced by 1.67 times.
Conclusion. The episodic use of Valvir (valacyclovir) in patients with recurrent genital herpes can statistically significantly reduce the severity and duration of the current relapse and provide psychological support for the patients.

Keywords

recurrent genital herpes
Valvir (valacyclovir)

Supplementary Materials

  1. Table. Monitoring of clinical symptoms of recurrent genital herpes on the background of causal antiviral therapy with Valvir

References

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Received 16.06.2017

Accepted 23.06.2017

About the Authors

Pestrikova Tatyana Yurievna, MD, professor, head of the Department of Obstetrics and Gynecology, Far Eastern State Medical University, Ministry of Health of Russia. 680000, Russia, Khabarovsk, Muravyeva-Amurskogo str. 35. Tel.: +74212305311, +79147719383. E-mail: typ50@rambler.ru
Yurasova Elena Anatolyevna, MD, Professor of the Department of Obstetrics and Gynecology, Far Eastern State Medical University, Ministry of Health of Russia.
680000, Russia, Khabarovsk, Muravyeva-Amurskogo str. 35. Tel.: +74212305311, +79625838255. E-mail: urasovaea@yandex.ru
Kovaleva Tamara Daniilovna, MD, Assistant of the Department of Obstetrics and Gynecology, Far Eastern State Medical University, Ministry of Health of Russia.
680000, Russia, Khabarovsk, Muravyeva-Amurskogo str. 35. Tel.: +79242120730. E-mail: kov-express@mail.ru
Voronova Yulia Vladimirovna, MD, associate professor of the Department of Obstetrics and Gynecology, Far Eastern State Medical University, Ministry of Health of Russia. 680000, Russia, Khabarovsk, Muravyeva-Amurskogo str. 35. Tel.: +79098411288. E-mail: yulyapankova @ rambler.ru
Kotelnikova Anastasia Vladimirovna, Assistant of the Department of Obstetrics and Gynecology, Far Eastern State Medical University, Ministry of Health of Russia.
680000, Russia, Khabarovsk, Muravyeva-Amurskogo str. 35. Tel.: +74212305311, +79145407860. E-mail: tempo-m@mail.ru

For citations: Pestrikova T.Yu., Yurasova E.A., Kovaleva T.D., Voronova Yu.V., Kotelnikova A.V. Evaluation of the clinical efficiency of antiviral therapy for recurrent genital herpes. Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2017; (9): 127-31. (in Russian)
http://dx.doi.org/10.18565/aig.2017.9.127-31
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