Polycystic ovary syndrome and pregnancy

Ananyev E.V.

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia, Moscow 117997, Ac. Oparina str. 4, Russia
Objective. To carry out a systematic analysis of the data given in the current literature on obstetric complications in women with polycystic ovary syndrome (PCOS).
Materials and methods. The review includes the data of foreign and Russian studies, which have been published in the electronic databases Medline, PubMed, and Cochrane Library over the past 10 years.
Results. The given review considers data on pregnancy complications in PCOS, such as miscarriage, multiple pregnancy, gestational hypertension and preeclampsia, gestational diabetes, birth of premature babies and macrosomic ones, as well as some pathophysiological processes that may underlie these complications.
Conclusion. Hyperandrogenia, insulin resistance, obesity, and dyslipidemia, which are characteristic of PCOS, are likely to be crucial factors for the processes of trophoblast invasion and placentation and can affect the health of mother and child. Pregravid counseling in women with PCOS and close monitoring during pregnancy are recommended to prevent adverse pregnancy outcomes.

Keywords

polycystic ovary syndrome
hyperandrogenia
insulin resistance
miscarriage
gestational diabetes
hypertension
preeclampsia

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Received 20.12.2016

Accepted 23.12.2016

About the Authors

Ananyev E.V., senior researcher of maternity department, Research Center of Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia.
117997, Russia, Moscow, Ac. Oparina str. 4. Tel.: +79857679777. E-mail: new_vision@mail.ru

For citations: Ananyev E.V. Polycystic ovary syndrome and pregnancy.
Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2017; (9): 5-11. (in Russian)
http://dx.doi.org/10.18565/aig.2017.9.5-11

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