A new approach to treating bacterial vaginosis

Khryanin A.A., Reshetnikov O.V.

1Novosibirsk State Medical University, Ministry of Health of Russia, Novosibirsk 630091, Krasny prospect, 52, Russia 2Regional Public Organization “Association of Obstetricians/Gynecologists and Dermatovenereologists”, Novosibirsk 3Research Institute of Therapy and Preventive Medicine, Novosibirsk 630089, B. Bogatkova str. 175/1, Russia
Objective. To carry out a systematic analysis of the data available in the current literature on the efficacy of lactic-acid bacteria, Lactobacillus strains in particular, in treating bacterial vaginosis.
Material and methods. The review includes the data of foreign and Russian articles published in the past 10 years and found on this topic.
Results. The paper analyzes the results of the found studies of the efficacy and safety of lactic acid bacteria-containing agents in the treatment of bacterial vaginosis. Their evidence level is estimated.
Conclusion. It is concluded that Provag containing Lactobacillus strains has a clinical effect and safety, which enable its use to be recommended for the treatment of recurrent bacterial vaginosis and aerobic vaginitis. At the same time the drug is also effective in treating other diseases associated with these conditions, papillomavirus infection in particular.

Keywords

bacterial vaginosis
lactic acid bacteria
Lactobacillus strains
provag

Supplementary Materials

  1. Table. Microscopic characteristics of the vaginal biocenosis (EF Kira, 1995)

References

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3. Khryanin A.A., Reshetnikov O.V. Bacterial vaginosis: A new paradigm. Akusherstvo i ginekologiya/Obstetrics and Gynecology. 2016; (4): 133-139. (in Russian) http://dx.doi.org/10.18565/aig.2016.4.133-139

4. Levakov S.A., Kedrova A.G., Chelnokova N.N. The use of modern strains of Lactobacillus in the treatment of bacterial vaginosis in premenopausal women. Problemyi reproduktsii. 2013; 19(2): 91-4. (in Russian)

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Received 21.04.2017

Accepted 28.04.2017

About the Authors

Khryanin Alexey Alexeevich, MD, Professor of the Department of Dermatovenereology and Cosmetology, Novosibirsk State Medical University, Ministry of Health of Russia; Vice-President of the Regional Public Organization “Association of Obstetricians/Gynecologists and Dermatovenereologists”.
630091, Russia, Novosibirsk, Krasny prospect, 52. E-mail: khryanin@mail.ru
Reshetnikov Oleg Vadimovich, doctor of medical sciences, leading researcher of the Research Institute of Therapy and Preventive Medicine,
Siberian Branch of the Russian Academy of Medical Sciences. 630089, Russia, Novosibirsk, B. Bogatkova str. 175/1. E-mail: reshetnikov_ov@mail.ru

For citations: Khryanin A.A., Reshetnikov O.V. A new approach to treating bacterial vaginosis. Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2017; (6): 159-64. (in Russian)
http://dx.doi.org/10.18565/aig.2017.6.159-64

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