Menopausal hormone therapy and risk of coronary heart disease

Yureneva S.V., Ilyina L.M.

1Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia, Moscow 117997, Ac. Oparina str. 4, Russia 2Association of Gynecological Endocrinologists, Moscow, Russia
Objective. To analyze the data available in the modern literature on the impact of menopausal hormone therapy (MHT) on the risk of coronary heart disease (CHD) in the postmenopause.
Material and methods. The review includes the data of foreign and Russian articles published mainly in the past 5 years and found in Pubmed on this topic.
Results. Different manifestations of CHD in women versus men, the cardiovascular benefits of MHT, and the current view of its characteristics in the light of the benefit-risk balance were described.
Conclusion. MHT is not a standard therapy for any woman and her cardiovascular risks may be minimal and the benefits may be maximal when choosing the optimal therapy option.

Keywords

postmenopause
coronary heart disease
menopausal hormone therapy
benefit-risk balance

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Received 07.02.2017

Accepted 17.02.2017

About the Authors

Yureneva Svetlana Vladimirovna, MD, senior researcher in Department of gynecological endocrinology of Research Center of Obstetrics, Gynecology,
and Perinatology, Ministry of Health of Russia. 117997, Russia, Moscow, Ac. Oparina str. 4. Tel.: +79161797400. E-mail: syureneva@gmail.com
Ilina Lilia Mikhailovna, PhD, secretary of Association of gynecologists and endocrinologists.
117997, Russia, Moscow, Ac. Oparina str. 4. Tel.: +79152101931. E-mail: bseiljina@mail.ru

For citations: Yureneva S.V., Ilyina L.M.
Menopausal hormone therapy and risk of coronary heart disease.
Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2017; (3): 42-9. (in Russian)
http://dx.doi.org/10.18565/aig.2017.3.42-9

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